Professor
SHIH, David Jen Hao

Background

Dr. Shih completed his BSc, MSc, and PhD at the University of Toronto, and he undertook postdoctoral training in the Department of Data Science at Dana-Farber Cancer Institute, with cross-appointments in the Department of Biostatistics at Harvard T.H. School of Public Health and in the Cancer Program at the Broad Institute. He also did a postdoctoral fellowship in Systems Biology at MD Anderson Cancer Institute. Prior to joining HKU, Dr. Shih was a Research Assistant Professor in the School of Biomedical Informatics at the University of Texas Health Science Center, while serving as Co-Director of the Data Science and Informatics Core for Cancer Research.

In his past research, Dr. Shih characterized the genomics of pediatric brain tumors in order to identify molecular subtypes of cancer, cancer driver genes, aberrant molecular pathways, and prognostic biomarkers. He studied the molecular evolution of brain metastases and developed novel methodologies for comparative DNA copy-number analysis. He also investigated therapeutic strategies to exploit cancer defects in DNA damage repair using pharmacogenomic data. Additionally, he also performed longitudinal studies using electronic health records and sequencing data in order to better understand cancer progression and immune response. Above all, Dr. Shih collaborates extensively with scientists and clinicians around the world.